diff --git a/Marlin/src/inc/SanityCheck.h b/Marlin/src/inc/SanityCheck.h
index d37f16b22..26b7c8a5c 100644
--- a/Marlin/src/inc/SanityCheck.h
+++ b/Marlin/src/inc/SanityCheck.h
@@ -582,8 +582,12 @@ static_assert(X_MAX_LENGTH >= X_BED_SIZE && Y_MAX_LENGTH >= Y_BED_SIZE,
 /**
  * Single Stepper Dual Extruder with switching servo
  */
-#if ENABLED(SWITCHING_EXTRUDER) && NUM_SERVOS < 1
-  #error "SWITCHING_EXTRUDER requires NUM_SERVOS >= 1."
+#if ENABLED(SWITCHING_EXTRUDER)
+  #if ENABLED(SINGLENOZZLE)
+    #error "SWITCHING_EXTRUDER and SINGLENOZZLE are incompatible."
+  #elif NUM_SERVOS < 1
+    #error "SWITCHING_EXTRUDER requires NUM_SERVOS >= 1."
+  #endif
 #endif
 
 /**