diff --git a/Marlin/stepper.h b/Marlin/stepper.h
index 8eb701662..1dfe79bfc 100644
--- a/Marlin/stepper.h
+++ b/Marlin/stepper.h
@@ -24,31 +24,6 @@
 #include "planner.h"
 #include "stepper_indirection.h"
 
-#if EXTRUDERS > 3
-  #define E_STEP_WRITE(v) { if(current_block->active_extruder == 3) { E3_STEP_WRITE(v); } else { if(current_block->active_extruder == 2) { E2_STEP_WRITE(v); } else { if(current_block->active_extruder == 1) { E1_STEP_WRITE(v); } else { E0_STEP_WRITE(v); }}}}
-  #define NORM_E_DIR() { if(current_block->active_extruder == 3) { E3_DIR_WRITE( !INVERT_E3_DIR); } else { if(current_block->active_extruder == 2) { E2_DIR_WRITE(!INVERT_E2_DIR); } else { if(current_block->active_extruder == 1) { E1_DIR_WRITE(!INVERT_E1_DIR); } else { E0_DIR_WRITE(!INVERT_E0_DIR); }}}}
-  #define REV_E_DIR() { if(current_block->active_extruder == 3) { E3_DIR_WRITE(INVERT_E3_DIR); } else { if(current_block->active_extruder == 2) { E2_DIR_WRITE(INVERT_E2_DIR); } else { if(current_block->active_extruder == 1) { E1_DIR_WRITE(INVERT_E1_DIR); } else { E0_DIR_WRITE(INVERT_E0_DIR); }}}}
-#elif EXTRUDERS > 2
-  #define E_STEP_WRITE(v) { if(current_block->active_extruder == 2) { E2_STEP_WRITE(v); } else { if(current_block->active_extruder == 1) { E1_STEP_WRITE(v); } else { E0_STEP_WRITE(v); }}}
-  #define NORM_E_DIR() { if(current_block->active_extruder == 2) { E2_DIR_WRITE(!INVERT_E2_DIR); } else { if(current_block->active_extruder == 1) { E1_DIR_WRITE(!INVERT_E1_DIR); } else { E0_DIR_WRITE(!INVERT_E0_DIR); }}}
-  #define REV_E_DIR() { if(current_block->active_extruder == 2) { E2_DIR_WRITE(INVERT_E2_DIR); } else { if(current_block->active_extruder == 1) { E1_DIR_WRITE(INVERT_E1_DIR); } else { E0_DIR_WRITE(INVERT_E0_DIR); }}}
-#elif EXTRUDERS > 1
-  #if DISABLED(DUAL_X_CARRIAGE)
-    #define E_STEP_WRITE(v) { if(current_block->active_extruder == 1) { E1_STEP_WRITE(v); } else { E0_STEP_WRITE(v); }}
-    #define NORM_E_DIR() { if(current_block->active_extruder == 1) { E1_DIR_WRITE(!INVERT_E1_DIR); } else { E0_DIR_WRITE(!INVERT_E0_DIR); }}
-    #define REV_E_DIR() { if(current_block->active_extruder == 1) { E1_DIR_WRITE(INVERT_E1_DIR); } else { E0_DIR_WRITE(INVERT_E0_DIR); }}
-  #else
-    extern bool extruder_duplication_enabled;
-    #define E_STEP_WRITE(v) { if(extruder_duplication_enabled) { E0_STEP_WRITE(v); E1_STEP_WRITE(v); } else if(current_block->active_extruder == 1) { E1_STEP_WRITE(v); } else { E0_STEP_WRITE(v); }}
-    #define NORM_E_DIR() { if(extruder_duplication_enabled) { E0_DIR_WRITE(!INVERT_E0_DIR); E1_DIR_WRITE(!INVERT_E1_DIR); } else if(current_block->active_extruder == 1) { E1_DIR_WRITE(!INVERT_E1_DIR); } else { E0_DIR_WRITE(!INVERT_E0_DIR); }}
-    #define REV_E_DIR() { if(extruder_duplication_enabled) { E0_DIR_WRITE(INVERT_E0_DIR); E1_DIR_WRITE(INVERT_E1_DIR); } else if(current_block->active_extruder == 1) { E1_DIR_WRITE(INVERT_E1_DIR); } else { E0_DIR_WRITE(INVERT_E0_DIR); }}
-  #endif
-#else
-  #define E_STEP_WRITE(v) E0_STEP_WRITE(v)
-  #define NORM_E_DIR() E0_DIR_WRITE(!INVERT_E0_DIR)
-  #define REV_E_DIR() E0_DIR_WRITE(INVERT_E0_DIR)
-#endif
-
 #if ENABLED(ABORT_ON_ENDSTOP_HIT_FEATURE_ENABLED)
   extern bool abort_on_endstop_hit;
 #endif
diff --git a/Marlin/stepper_indirection.h b/Marlin/stepper_indirection.h
index 8341aa040..f719fecc3 100644
--- a/Marlin/stepper_indirection.h
+++ b/Marlin/stepper_indirection.h
@@ -154,6 +154,34 @@
 #define E3_ENABLE_WRITE(STATE) WRITE(E3_ENABLE_PIN,STATE)
 #define E3_ENABLE_READ READ(E3_ENABLE_PIN)
 
+#if EXTRUDERS > 3
+  #define E_STEP_WRITE(v) {switch(current_block->active_extruder){case 3:E3_STEP_WRITE(v);break;case 2:E2_STEP_WRITE(v);break;case 1:E1_STEP_WRITE(v);break;default:E0_STEP_WRITE(v);}}
+  #define NORM_E_DIR() {switch(current_block->active_extruder){case 3:E3_DIR_WRITE(!INVERT_E3_DIR);break;case 2:E2_DIR_WRITE(!INVERT_E2_DIR);break;case 1:E1_DIR_WRITE(!INVERT_E1_DIR);break;default:E0_DIR_WRITE(!INVERT_E0_DIR);}}
+  #define REV_E_DIR() {switch(current_block->active_extruder){case 3:E3_DIR_WRITE(INVERT_E3_DIR);break;case 2:E2_DIR_WRITE(INVERT_E2_DIR);break;case 1:E1_DIR_WRITE(INVERT_E1_DIR);break;default:E0_DIR_WRITE(INVERT_E0_DIR);}}
+#elif EXTRUDERS > 2
+  #define E_STEP_WRITE(v) {switch(current_block->active_extruder){case 2:E2_STEP_WRITE(v);break;case 1:E1_STEP_WRITE(v);break;default:E0_STEP_WRITE(v);}}
+  #define NORM_E_DIR() {switch(current_block->active_extruder){case 2:E2_DIR_WRITE(!INVERT_E2_DIR);break;case 1:E1_DIR_WRITE(!INVERT_E1_DIR);break;default:E0_DIR_WRITE(!INVERT_E0_DIR);}}
+  #define REV_E_DIR() {switch(current_block->active_extruder){case 2:E2_DIR_WRITE(INVERT_E2_DIR);break;case 1:E1_DIR_WRITE(INVERT_E1_DIR);break;default:E0_DIR_WRITE(INVERT_E0_DIR);}}
+#elif EXTRUDERS > 1
+  #define _E_STEP_WRITE(v) {if(current_block->active_extruder==1){E1_STEP_WRITE(v);}else{E0_STEP_WRITE(v);}}
+  #define _NORM_E_DIR() {if(current_block->active_extruder==1){E1_DIR_WRITE(!INVERT_E1_DIR);}else{E0_DIR_WRITE(!INVERT_E0_DIR);}}
+  #define _REV_E_DIR() {if(current_block->active_extruder==1){E1_DIR_WRITE(INVERT_E1_DIR);}else{E0_DIR_WRITE(INVERT_E0_DIR);}}
+  #if DISABLED(DUAL_X_CARRIAGE)
+    #define E_STEP_WRITE(v) _E_STEP_WRITE(v)
+    #define NORM_E_DIR() _NORM_E_DIR()
+    #define REV_E_DIR() _REV_E_DIR()
+  #else
+    extern bool extruder_duplication_enabled;
+    #define E_STEP_WRITE(v) {if(extruder_duplication_enabled){E0_STEP_WRITE(v);E1_STEP_WRITE(v);}else _E_STEP_WRITE(v);}
+    #define NORM_E_DIR() {if(extruder_duplication_enabled){E0_DIR_WRITE(!INVERT_E0_DIR);E1_DIR_WRITE(!INVERT_E1_DIR);}else _NORM_E_DIR();}
+    #define REV_E_DIR() {if(extruder_duplication_enabled){E0_DIR_WRITE(INVERT_E0_DIR);E1_DIR_WRITE(INVERT_E1_DIR);}else _REV_E_DIR();}
+  #endif
+#else
+  #define E_STEP_WRITE(v) E0_STEP_WRITE(v)
+  #define NORM_E_DIR() E0_DIR_WRITE(!INVERT_E0_DIR)
+  #define REV_E_DIR() E0_DIR_WRITE(INVERT_E0_DIR)
+#endif
+
 //////////////////////////////////
 // Pin redefines for TMC drivers.
 // TMC26X drivers have step and dir on normal pins, but everything else via SPI