diff --git a/Marlin/src/feature/twibus.cpp b/Marlin/src/feature/twibus.cpp
index 60d78018a..9dbb1deb4 100644
--- a/Marlin/src/feature/twibus.cpp
+++ b/Marlin/src/feature/twibus.cpp
@@ -49,37 +49,27 @@ void TWIBus::address(const uint8_t adr) {
 
   addr = adr;
 
-  #if ENABLED(DEBUG_TWIBUS)
-    debug(PSTR("address"), adr);
-  #endif
+  debug(PSTR("address"), adr);
 }
 
 void TWIBus::addbyte(const char c) {
   if (buffer_s >= COUNT(buffer)) return;
   buffer[buffer_s++] = c;
-  #if ENABLED(DEBUG_TWIBUS)
-    debug(PSTR("addbyte"), c);
-  #endif
+  debug(PSTR("addbyte"), c);
 }
 
 void TWIBus::addbytes(char src[], uint8_t bytes) {
-  #if ENABLED(DEBUG_TWIBUS)
-    debug(PSTR("addbytes"), bytes);
-  #endif
+  debug(PSTR("addbytes"), bytes);
   while (bytes--) addbyte(*src++);
 }
 
 void TWIBus::addstring(char str[]) {
-  #if ENABLED(DEBUG_TWIBUS)
-    debug(PSTR("addstring"), str);
-  #endif
+  debug(PSTR("addstring"), str);
   while (char c = *str++) addbyte(c);
 }
 
 void TWIBus::send() {
-  #if ENABLED(DEBUG_TWIBUS)
-    debug(PSTR("send"), addr);
-  #endif
+  debug(PSTR("send"), addr);
 
   Wire.beginTransmission(I2C_ADDRESS(addr));
   Wire.write(buffer, buffer_s);
@@ -89,21 +79,21 @@ void TWIBus::send() {
 }
 
 // static
-void TWIBus::echoprefix(uint8_t bytes, const char prefix[], uint8_t adr) {
+void TWIBus::echoprefix(uint8_t bytes, const char pref[], uint8_t adr) {
   SERIAL_ECHO_START();
-  serialprintPGM(prefix);
+  serialprintPGM(pref);
   SERIAL_ECHOPAIR(": from:", adr, " bytes:", bytes, " data:");
 }
 
 // static
-void TWIBus::echodata(uint8_t bytes, const char prefix[], uint8_t adr) {
-  echoprefix(bytes, prefix, adr);
+void TWIBus::echodata(uint8_t bytes, const char pref[], uint8_t adr) {
+  echoprefix(bytes, pref, adr);
   while (bytes-- && Wire.available()) SERIAL_CHAR(Wire.read());
   SERIAL_EOL();
 }
 
-void TWIBus::echobuffer(const char prefix[], uint8_t adr) {
-  echoprefix(buffer_s, prefix, adr);
+void TWIBus::echobuffer(const char pref[], uint8_t adr) {
+  echoprefix(buffer_s, pref, adr);
   LOOP_L_N(i, buffer_s) SERIAL_CHAR(buffer[i]);
   SERIAL_EOL();
 }
@@ -111,15 +101,11 @@ void TWIBus::echobuffer(const char prefix[], uint8_t adr) {
 bool TWIBus::request(const uint8_t bytes) {
   if (!addr) return false;
 
-  #if ENABLED(DEBUG_TWIBUS)
-    debug(PSTR("request"), bytes);
-  #endif
+  debug(PSTR("request"), bytes);
 
   // requestFrom() is a blocking function
   if (Wire.requestFrom(addr, bytes) == 0) {
-    #if ENABLED(DEBUG_TWIBUS)
-      debug("request fail", addr);
-    #endif
+    debug("request fail", addr);
     return false;
   }
 
@@ -127,9 +113,7 @@ bool TWIBus::request(const uint8_t bytes) {
 }
 
 void TWIBus::relay(const uint8_t bytes) {
-  #if ENABLED(DEBUG_TWIBUS)
-    debug(PSTR("relay"), bytes);
-  #endif
+  debug(PSTR("relay"), bytes);
 
   if (request(bytes))
     echodata(bytes, PSTR("i2c-reply"), addr);
@@ -141,9 +125,7 @@ uint8_t TWIBus::capture(char *dst, const uint8_t bytes) {
   while (count < bytes && Wire.available())
     dst[count++] = Wire.read();
 
-  #if ENABLED(DEBUG_TWIBUS)
-    debug(PSTR("capture"), count);
-  #endif
+  debug(PSTR("capture"), count);
 
   return count;
 }
@@ -156,16 +138,12 @@ void TWIBus::flush() {
 #if I2C_SLAVE_ADDRESS > 0
 
   void TWIBus::receive(uint8_t bytes) {
-    #if ENABLED(DEBUG_TWIBUS)
-      debug(PSTR("receive"), bytes);
-    #endif
+    debug(PSTR("receive"), bytes);
     echodata(bytes, PSTR("i2c-receive"), 0);
   }
 
   void TWIBus::reply(char str[]/*=nullptr*/) {
-    #if ENABLED(DEBUG_TWIBUS)
-      debug(PSTR("reply"), str);
-    #endif
+    debug(PSTR("reply"), str);
 
     if (str) {
       reset();
diff --git a/Marlin/src/feature/twibus.h b/Marlin/src/feature/twibus.h
index faf9eb38c..2c1b20da5 100644
--- a/Marlin/src/feature/twibus.h
+++ b/Marlin/src/feature/twibus.h
@@ -223,7 +223,6 @@ class TWIBus {
     #endif
 
     #if ENABLED(DEBUG_TWIBUS)
-
       /**
        * @brief Prints a debug message
        * @details Prints a simple debug message "TWIBus::function: value"
@@ -233,6 +232,10 @@ class TWIBus {
       static void debug(const char func[], char c);
       static void debug(const char func[], char adr[]);
       static inline void debug(const char func[], uint8_t v) { debug(func, (uint32_t)v); }
-
+    #else
+      static inline void debug(const char[], uint32_t) {}
+      static inline void debug(const char[], char) {}
+      static inline void debug(const char[], char[]) {}
+      static inline void debug(const char[], uint8_t) {}
     #endif
 };