diff --git a/Marlin/SanityCheck.h b/Marlin/SanityCheck.h
index c2b189037..8d5f4a317 100644
--- a/Marlin/SanityCheck.h
+++ b/Marlin/SanityCheck.h
@@ -117,6 +117,13 @@
   #error EXTRUDER_RUNOUT_PREVENT currently incompatible with FILAMENTCHANGE.
 #endif
 
+/**
+ * Individual axis homing is useless for DELTAS
+ */
+#if ENABLED(INDIVIDUAL_AXIS_HOMING_MENU) && ENABLED(DELTA)
+  #error Individual axis homing will not work with a DELTA kinematics.
+#endif
+
 /**
  * Options only for EXTRUDERS > 1
  */